Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response
نویسندگان
چکیده
منابع مشابه
Intracellular osteopontin stabilizes TRAF3 to positively regulate innate antiviral response
Osteopontin (OPN) is a multifunctional protein involved in both innate immunity and adaptive immunity. However, the function of OPN, especially the intracellular form OPN (iOPN) on innate antiviral immune response remains elusive. Here, we demonstrated that iOPN is an essential positive regulator to protect the host from virus infection. OPN deficiency or knockdown significantly attenuated viru...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep23771